Pharmacology

.IO is a 69 yo receiving digoxin for atrial fibrillation. He intentionally took an OD of the medication. What is the role for digoxin immune fab fragments (digibind or dififab)? What are the signs and symptoms of digoxin toxicity? How can one predict severity of a dig overdose?
2.BL is a 69 yo with CHF. What is the role of using an ACE or ARB in Congestive Heart failure?
When would you suggest a Beta Blocker? Which Beta Blocker would you suggest?
3.OL a 4 yo receiving digoxin for a congenital heart disease. The child now has an infection and erythromycin was started. Is there an interaction between the 2? If so, please explain the mechanism and how long after starting the erythromycin would it been seen?
4.Spironolactone and eplerenone in treating those with CHF. Based upon journal articles you find (not a textbook), should patients with CHF receive Spironolactone or eplerenone. Why or why not? your ref.?
5.KI is a 78 yo being treated with bumetanide 2 mg orally every day. He is now NPO. (nothing by mouth) What would be the appropriate starting IV dose and why?
What are the monitoring parameters of efficacy and toxicity of it?
6.What oral hypoglycemics have been associated with worsening of edema and worsening CHF?